Clinical microbiomics

Find novel biomarkers!

Microbes in health
clinical-microbiomicsIdentification of compositional shifts or changes of the microbiome and microbial pathways with human health status can be challenging. Analysis of the enormous amount of data from next-generation sequencing presents a bottleneck in clinical research of the human microbiome. With our sophisticated bioinformatic analysis pipelines, we deliver comprehensive analysis service of the microbiome for data derived from

  • 16S rDNA/ rRNA amplicons
  • Shotgun metagenomics
  • Shotgun metatranscriptomics

for the growing number of clinical trials. Using model-based multivariate statistics, we identify biomarkers corresponding to your study design. This will help you to find:

  • new targets for medical treatment
  • new treatment strategies
  • links between microbial composition and diseases
  • microbial indicator species
  • treatment-specific enriched microbial genes and pathways
  • clinical parameter and microbial dynamics

For academic clients we procure sequencing of amplicon or shotgun libraries on Illumina® MiSeq™ and NextSeq™ platforms. Our scientists and partners have long-term experience in human microbiome research, including:

  • Conception of study designs
  • Probiotics
  • Prebiotics
  • Antibiotics
  • Nutrition
  • “Healthy” gut microbiome
  • Infectious diseases
    (e.g., Sarcoidosis, Clostridium difficile-Associated Diarrhea)
  • Fecal transplantation
  • Microbe-cancer interrelation

Our experts will be happy to discuss your personal clinical microbiome project.