Clinical microbiomics
Find novel biomarkers!
Microbes in health
Identification of compositional shifts or changes of the microbiome and microbial pathways with human health status can be challenging. Analysis of the enormous amount of data from next-generation sequencing presents a bottleneck in clinical research of the human microbiome. With our sophisticated bioinformatic analysis pipelines, we deliver comprehensive analysis service of the microbiome for data derived from
- 16S rDNA/ rRNA amplicons
- Shotgun metagenomics
- Shotgun metatranscriptomics
for the growing number of clinical trials. Using model-based multivariate statistics, we identify biomarkers corresponding to your study design. This will help you to find:
- new targets for medical treatment
- new treatment strategies
- links between microbial composition and diseases
- microbial indicator species
- treatment-specific enriched microbial genes and pathways
- clinical parameter and microbial dynamics
For academic clients we procure sequencing of amplicon or shotgun libraries on Illumina® MiSeq™ and NextSeq™ platforms. Our scientists and partners have long-term experience in human microbiome research, including:
- Conception of study designs
- Probiotics
- Prebiotics
- Antibiotics
- Nutrition
- “Healthy” gut microbiome
- Infectious diseases
(e.g., Sarcoidosis, Clostridium difficile-Associated Diarrhea) - Fecal transplantation
- Microbe-cancer interrelation
Our experts will be happy to discuss your personal clinical microbiome project.
